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FOR ADULT CONSUMERS 18+ ONLY
Enhanced does not manufacture compounded medications. Actual product appearance and labeling of the medication you receive will differ from website images
What GHK-Cu May Support
What the Science Says
Firmer Look
May support the appearance of firmer, more elastic-looking skin [1]
Collagen Support
Studied for its role in supporting collagen and elastin processes [2]
Smoother texture
Users may report smoother, more refined-looking skin texture [3]
Antioxidant
Copper peptides have been studied for antioxidant activity [4]
What is GHK-Cu?
A naturally occurring copper-binding peptide your body already makes.
GHK-Cu is a tripeptide-copper complex made of three amino acids - glycine, histidine, lysine - bound to a copper ion. It was first identified in human plasma in 1973 and has been studied extensively since.
EDUCATIONAL INFORMATION. GHK-CU IS A WELL-STUDIED COSMETIC PEPTIDE. ENHANCED GHK-CU IS A TOPICAL SERUM, NOT A DRUG OR MEDICAL DEVICE. ALWAYS PATCH TEST BEFORE REGULAR USE. [1] PICKART L. FEBS LETT. 1973;104(1):119-122
Identified in human blood plasma by Dr. Loren Pickart while researching age-related changes.
Hundreds of peer-reviewed papers explore its role in skin remodeling, antioxidant activity, and tissue repair.
A staple ingredient in clinical-grade skincare formulations worldwide for over 20 years.
Compounded by trusted US-licensed pharmacies at high quality dosages.
What to expect
Your first 6 months
WEEKS 1-2
Skin may begin to feel smoother and more hydrated.
Some users report immediate improvements in how their skin looks first thing in the morning.
WEEKS 4-6
Texture refinement may become more noticeable [1].
Users may report subtle improvements in firmness and overall complexion.
MONTHS 2-3
Studies suggest visible benefits to fine lines and skin elasticity may become more apparent with consistent twice-daily use [2].
MONTHS 3-6
Sustained use may continue to support the appearance of healthier-looking, more resilient skin [3].
Consistency matters. GHK-Cu rewards routine. Daily application, sun protection, sleep, and hydration amplify visible results.
INDIVIDUAL RESULTS MAY VARY. TIMELINES ARE BASED ON PUBLISHED CLINICAL LITERATURE FOR TOPICAL COPPER PEPTIDE FORMULATIONS. YOUR RESULTS DEPEND ON SKIN TYPE, AGE, SUN EXPOSURE, BASELINE SKIN CONDITION, AND ADHERENCE.
[1] LEYDEN J, ET AL. AM ACAD DERMATOL MTG. 2002
[2] ABDULGHANI AA, ET AL. J DERMATOL TREAT. 1998; 9(4): 239-246
[3] PICKART L, MARGOLINA A. INT J MOL SCI. 2018:19(7) :1987
FOR THE LOOKSMAXXING ERA
Caring how you look has gone mainstream. The smartest people in the conversation are the ones doing it with evidence.
looking after your appearance isn't vanity, it's maintenance.
THE EVIDENCE - BASED STACK
GHK-Cu sits in a small category of ingredients that have actually earned their reputation - decades of peer-reviewed research, a clear mechanism, and a strong topical safety profile 1). That's why it keeps showing up in serious skincare conversations.
7-9 hours. Free. Non-negotiable.
Daily SPF. The single highest-leverage habit.
Protein, hydration, micronutrients. The basics matter.
For a tighter, firmer look
General Member Outcomes
Real Results, Verified Members
"Proven by
Bloodwork"
Enhanced has been a great experience, from ease of use to quick and responsive customer support. Scheduling blood tests, getting the results, and meeting with the clinician has been seamless. I've noticed a difference in energy and strength since being on enclomiphene, the best part is I have the bloodwork to support it.
Cesar, 24
"Easy at
Home"
I've been using the longevity protocols for close to a month now and it's been a really positive experience. The injections are quick, painless, and super simple to do at home. No negative side effects at all, which is awesome! Customer support has been excellent from day one, medication shipped fast and arrived perfectly...
The Science
In controlled studies, GHK-Cu was associated with a 55.8% reduction in wrinkle volume and 32.8% reduction in wrinkle depth compared to control groups. It has also been shown to modulate over 4,000 human genes, many of which are involved in DNA repair and tissue maintenance.
Sources: Pickart et al., Int. J. Mol. Sci. (2018); Abdulghani et al., J. Cosmet. Dermatol. (2018); Broad Institute Connectivity Map analysis.
Who This is For
GHK-Cu is a naturally occurring peptide involved in collagen production and tissue regeneration. Your body already uses it. Enhanced delivers it at concentrations designed to do more.
Caring how you look has gone mainstream. The smartest people in the conversation are the ones doing it with evidence. GHK-Cu sits in a small category of ingredients that have actually earned their reputation - decades of peer-reviewed research, a clear mechanism, and a strong topical safety profile 1). That's why it keeps showing up in serious skincare conversations.
Your face finally matches the work you put into your body
Your skin's recovery timeline, optimized
Clinical Advisory
The Expert Advisors
Dr. Jonathann Kuo, MD
Extension Health | CEO
Regenerative & Longevity medicine
Over 50,000 patients treated
Treats elite athletes, CEOs, and celebrities
Dr. Abud Bakri, MD
Health Optimization Expert
“One of the most forward thinking, valuable protocol offering MDs”
– Andrew D. Huberman, Ph.D. (@hubermanlab)
Dr. Paulina & Elena Rueda
Dama Health | Co-Founders
Forefront of advancing women's care
Personalized, data-driven protocols
150+ clinical data points assessed
Support
Collagen Production
Research suggests GHK-Cu may help support collagen I and III synthesis, which is associated with improved skin structure over time.
Support
Recovery Timelines
Studies have associated GHK-Cu with supporting faster healing across multiple tissue types.
Support
Hair Health
GHK-Cu may help support hair follicle function and scalp blood flow, which are associated with healthier growth cycles.
Complete your checkout
step
1
Complete your checkout and answer a short health questionnaire to help us understand your symptoms and goals.
Review with a clinician
step
2
A licensed clinician reviews your information.
Begin your treatment plan
step
3
If appropriate, receive a tailored plan with ongoing support and monitoring.
Everything you need to know.
Frequently asked questions
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